Transforming growth factor beta receptor expression in hyperstimulated human granulosa cells and cleavage potential

S K Roy1, S G Kurz, A M Carlson

  • 1Departments of Obstetrics and Gynecology, Olson's Center for Women's Health, Unversity of Nebraska Medical Center, Omaha, USA.

Biology of Reproduction
|November 26, 1998
PubMed

A possible relationship between transforming growth factor beta receptor type I (TbetaRI) and type II (TbetaRII) protein expression in human granulosa cells and the quality of preimplantation embryo development in vitro was studied using immunoblot analysis of TbetaRI and TbetaRII in hyperstimulated granulosa cells and morphological assessment of the cleavage potential of the zygotes in vitro. Washed granulosa cells were collected from