Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatic venous outflow obstruction

G K Pande1, C Srinath, S Pal

  • 1Department of Gastrointestinal Surgery and Liver Transplantation, All India Institute of Medical Sciences, New Delhi, India. gkpande@medinst.ernet.in

Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|November 26, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations of meteorological variability with sesame yield in semi-arid Bundelkhand region of India.

Scientific reports·2026
Same author

Floral and pollination biology of dragon fruit reveals strategies for enhancing productivity through pollination management and reproductive window extension.

Scientific reports·2025
Same author

Innovative and polygonal trend analysis of temperature in agro climatic zones of India.

Scientific reports·2024
Same author

Health effects of selected environmental Exposomes Across the Life courSe in Indian populations using longitudinal cohort studies: GEOHealth HEALS Study protocol.

BMJ open·2024
Same author

India led health innovation(s) for achieving the SDG health goal in the global South.

Perspectives in public health·2022
Same author

COVID-19: Impact analysis and recommendations for power sector operation.

Applied energy·2020
Same journal

ALPPS for a large hepatocellular carcinoma in hepatitis C patient.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
Same journal

Esophageal mucocele after surgical isolation of thoracic esophagus presenting with respiratory distress.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
Same journal

AMA-negative primary biliary cirrhosis in a young male.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
Same journal

Spontaneous perforation of an ileal J pouch.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
Same journal

Stapler hepatectomy in giant cavernous hemangioma of liver.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
Same journal

Multimodality imaging of gastric glomus tumor presenting with upper GI bleed.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2018
See all related articles

Budd-Chiari syndrome, a cause of portal hypertension, involves hepatic vein or IVC obstruction. Management includes anticoagulants, shunts, angioplasty, or transplantation, with potential for hepatocellular carcinoma development.

Area of Science:

  • Gastroenterology and Hepatology
  • Vascular Medicine
  • Hematology

Background:

  • Hepatic venous outflow obstruction, or Budd-Chiari syndrome, is an increasingly recognized cause of portal hypertension.
  • Obstruction patterns vary geographically, affecting hepatic veins in Western countries and the inferior vena cava (IVC) in South Africa, Japan, and India.
  • Etiologies include hypercoagulable states, but a cause remains unidentified in 25-75% of cases.

Purpose of the Study:

  • To provide a comprehensive overview of Budd-Chiari syndrome, encompassing its causes, clinical presentation, diagnostic modalities, and therapeutic strategies.
  • To highlight the importance of early diagnosis and appropriate management for improving patient outcomes.
  • To discuss the long-term complications, including hepatocellular carcinoma, and the role of anticoagulation.

Related Experiment Videos

Main Methods:

  • Review of existing literature on Budd-Chiari syndrome.
  • Analysis of diagnostic approaches, including ultrasound, liver biopsy, and imaging studies like inferior vena cavography.
  • Evaluation of treatment options, ranging from thrombolytic therapy and surgical shunts to balloon angioplasty and liver transplantation.

Main Results:

  • Hepatic vein obstruction typically presents with hepatomegaly and ascites, while IVC obstruction is associated with prominent superficial veins.
  • Ultrasound is the initial diagnostic step, with liver biopsy considered the gold standard.
  • Treatment strategies depend on the phase and severity, with anticoagulation crucial for preventing rethrombosis.

Conclusions:

  • Budd-Chiari syndrome requires a multi-faceted approach involving accurate diagnosis and tailored treatment.
  • Long-term anticoagulation is essential post-intervention to prevent recurrence.
  • Hepatocellular carcinoma is a significant long-term risk, necessitating vigilant follow-up.