Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Diffusion tensor analysis with nuclear magnetic resonance in human central nervous system]

N Nakayama1

  • 1Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan.

[Hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science
|November 26, 1998
PubMed
Summary

Nuclear magnetic resonance imaging quantifies water diffusion in the brain. Diffusion tensor analysis reveals neuronal fiber orientation and microstructural changes, offering insights into central nervous system function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic gain of the PRL-3 gene may represent poor prognosis of primary colorectal cancer, and associate with liver metastasis.

Clinical & experimental metastasis·2015
Same author

Therapy-related myelodysplastic syndrome and acute myeloid leukemia following chemotherapy (paclitaxel and carboplatin) and radiation therapy in ovarian cancer: a case report.

European journal of gynaecological oncology·2014
Same author

Surgical treatment outcomes of serious chronic tubo-ovarian abscess: a single-center series of 20 cases.

Clinical and experimental obstetrics & gynecology·2013
Same author

Pectic polysaccharides in carrot cells growing in suspension culture.

Planta·2013
Same author

Randomised phase II study of S-1/cisplatin plus TSU-68 vs S-1/cisplatin in patients with advanced gastric cancer.

British journal of cancer·2013
Same author

Perivascular epithelial cell tumor arising from polypoid adenomyoma: a case report.

European journal of gynaecological oncology·2013

Area of Science:

  • Neuroimaging
  • Biophysics
  • Diffusion MRI

Context:

  • Nuclear magnetic resonance (NMR) is a key technique for measuring water molecule diffusivity.
  • Anisotropic diffusion in the central nervous system (CNS) correlates with neuronal fiber tract orientation.
  • Accurate assessment of anisotropic diffusion requires determining the elements of the apparent diffusion tensor (Dapp).

Purpose:

  • To investigate practical procedures for analyzing the diffusion tensor (Dapp) using spin-echo and echo-planar diffusion-weighted imaging.
  • To evaluate the utility of different Dapp representations, such as diffusion ellipsoids, trace invariant values, and eigenvalue ratios.
  • To assess the application of diffusion tensor analysis in human brain imaging at 3-Tesla.

Summary:

  • Diffusion tensor analysis, using advanced MRI techniques, allows for the determination of principal diffusion directions and diffusivities.

Related Experiment Videos

  • The ellipsoid representation of diffusion tensors provides valuable microanatomical information, including fiber tract orientation and molecular mobility.
  • Observed loss of anisotropy in Wallerian degeneration lesions suggests diffusion tensor analysis can detect microstructural alterations and infer axonal function.

    • Impact:

    • Diffusion tensor analysis offers a powerful, noninvasive method for quantitative and functional evaluation of the central nervous system.
    • This technique aids in understanding microanatomy, neuronal connectivity, and pathological changes like Wallerian degeneration.
    • The findings support the potential of diffusion tensor imaging (DTI) as a diagnostic and research tool in neuroscience.