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[F-qi-FDG PET of the thyroid gland in Graves' disease]
A R Börner1, E Voth, K Wienhard
1Klinik und Poliklinik für Nuklearmedizin, Universität zu Köln. a.r.boerner@fz-juelich.de
Aim:
This study evaluates F-18-FDG PET of the thyroid in Graves' disease.
Methods:
Thirty patients were investigated the day before radioiodine therapy, 15 patients 3-10 days after radioiodine therapy. Twenty patients with cancer of the head or neck and normal thyroid function served as controls.
Results:
F-18-FDG uptake was higher in Graves' disease patients than in controls. Negative correlations of F-18-FDG uptake with half-life of radioiodine and absorbed radiation dose due to radioiodine therapy were found along with a positive correlation to autoantibody levels.
Conclusion:
Thus F-18-FDG PET is likely to give information on the biological activity of Graves' disease as well as on early radiation effects.