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[Integration of functional and morphologic MRI data for preoperative 3D visualization of tumors. Example: cervical
H Evers1, H Hawighorst, G van Kaick
1Abteilung Medizinische und Biologische Informatik, Deutsches Krebsforschungszentrum (dkfz), Heidelberg.
Purpose:
The goal of this exemplary study was to integrate morphological and functional MRI to establish computer-based, pre-operative therapy planning for tumors, instancing cervical carcinoma.
Methods:
For morphological representation T1-weighted, filtered 3D sequences were investigated within a hierarchical segmentation approach. Using a method for image registration, segmented structures were combined and overlaid with functional information of contrast medium-enhanced, dynamic MRI. After assigning colour attributes to the segmented structures, they were presented using a method for direct volume visualisation.
Results:
Segmentation of organs and vessels as well as tissue differentiation yielded a morphological visualisation of anatomical structures that were overlaid with pharmacokinetic parameters derived from dynamic MRI, subsequently. Thereby, three-dimensional, arbitrary views on the functional data were displayed.
Conclusions:
Image analysis and visualisation of the acquired MR data establishes both a morphologic and functional evaluation of suspect lesions and adjacent organs. By integrating morphologic and functional MRI additional information can be gathered that possibly impinge on preoperative planning.