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Related Experiment Videos

Patient regrets after bilateral prophylactic mastectomy

P I Borgen1, A D Hill, K N Tran

  • 1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. BorgenP@mskcc.org

Annals of Surgical Oncology
|November 27, 1998
PubMed
Summary

Most women are satisfied after prophylactic mastectomy, but physician-initiated discussions correlate with higher regret rates. Understanding patient-initiated discussions is key for favorable outcomes in prophylactic mastectomy decisions.

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Area of Science:

  • Oncology
  • Genetics
  • Surgery

Background:

  • Increased awareness of breast cancer susceptibility genes leads to more women seeking prophylactic mastectomy information.
  • Limited large-scale prospective data exists for women considering prophylactic mastectomy.

Purpose of the Study:

  • To assess satisfaction rates and identify factors influencing outcomes in women who have undergone prophylactic mastectomy.
  • To establish a database for women considering prophylactic mastectomy.

Main Methods:

  • A National Prophylactic Mastectomy Registry was created with 817 women from 43 states who underwent the procedure.
  • Data was collected on patient demographics, surgical history, and satisfaction levels.

Main Results:

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  • 95% of women reported satisfaction with bilateral prophylactic mastectomy.
  • Regret was more common when the discussion was initiated by a physician (19/255) compared to patient-initiated discussions (2/108).
  • Median follow-up was 14.6 years.

Conclusions:

  • The high satisfaction rate may be influenced by the voluntary nature of the registry.
  • Physician-initiated discussions are a significant predictor of unfavorable outcomes following bilateral prophylactic mastectomy.