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Tumour dose estimation using automated TLD techniques

H M Ferguson1, G D Lambert, D Gustard

  • 1Regional Medical Physics Department, Newcastle General Hospital, Newcastle-upon-Tyne, UK.

Acta Oncologica (Stockholm, Sweden)
|November 27, 1998
PubMed
Summary
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Lithium fluoride (TLD-700) dosimeters accurately measured radiation doses in radiotherapy. Delivered doses closely matched prescribed amounts, within approximately +/- 3% for various cancer treatments.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Dosimetry

Background:

  • Accurate absorbed dose delivery is crucial in external beam radiotherapy.
  • Lithium fluoride (TLD-700) dosimeters are commonly used for dose verification.

Purpose of the Study:

  • To assess the accuracy of delivered tumour absorbed doses using TLD-700 dosimeters.
  • To evaluate the detectability of International Commission on Radiation Units and Measurements (ICRU) recommended tolerances for dose delivery.

Main Methods:

  • Utilized automated TLD readers with TLD-700 dosimeters to measure exit surface absorbed doses.
  • Calculated delivered tumour absorbed doses for head and neck, pelvis, and breast radiotherapy treatments.
  • Analyzed the percentage difference between prescribed and delivered doses.

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Main Results:

  • Mean percentage differences between prescribed and delivered doses were within +/- 3% (1 SD) for all treatment sites.
  • The overall spread of results was approximately +/- 3% (1 SD).
  • This precision is comparable to the inherent uncertainty of TLD measurements (+/- 2%; 1 SD).

Conclusions:

  • The TLD-700 method demonstrated high accuracy in measuring delivered doses but may not detect ICRU-recommended +/- 5% tolerances.
  • An action level of +/- 10% is proposed for early detection of significant treatment delivery errors.
  • This approach allows for timely intervention before treatment completion, enabling dose compensation if necessary.