Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertransaminasaemia and Addison's disease

A Castiella1, X Etxeberria, J Ganzarain

  • 1Gastroenterology Unit, Mendaro Hospital, Guipuzcoa, Spain.

European Journal of Gastroenterology & Hepatology
|November 27, 1998
PubMed
Summary

This case study highlights a rare diagnosis of Addison's disease in a patient presenting with unexplained hypertransaminasaemia (elevated liver enzymes) and general symptoms. The findings emphasize the importance of considering uncommon endocrine disorders in differential diagnoses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Smart Healthy Age-Friendly Environments - Policy Recommendations of the Thematic Network <i>SHAFE</i>.

Translational medicine @ UniSa·2019
Same author

Health tourism: an opportunity for sustainable development.

Translational medicine @ UniSa·2019
Same author

Analysis of HFE mutations and non-HFE gene mutations (TFR2 and SLC40A1) in patients with phenotypic hemochromatosis from the Basque Country.

International journal of laboratory hematology·2015
Same author

Hepatotoxicity associated with statin use: analysis of the cases included in the Spanish Hepatotoxicity Registry.

Revista espanola de enfermedades digestivas·2014
Same author

Osseous metaplasia in a gastric adenomatous polyp.

Endoscopy·2012
Same author

Recurrent drug-induced liver injury (DILI) with different drugs in the Spanish Registry: the dilemma of the relationship to autoimmune hepatitis.

Journal of hepatology·2011

Area of Science:

  • Endocrinology
  • Hepatology

Background:

  • Hypertransaminasaemia is a common clinical finding with a broad differential diagnosis.
  • Addison's disease, or primary adrenal insufficiency, is an uncommon endocrine disorder.

Observation:

  • A 37-year-old male presented with hypertransaminasaemia, asthenia, anorexia, and weight loss.
  • Extensive investigations for common causes of elevated liver enzymes were negative.

Findings:

  • Addison's disease was diagnosed after ruling out other etiologies.
  • This represents a rare clinical association between hypertransaminasaemia and Addison's disease.

Implications:

  • Clinicians should consider rare endocrine disorders like Addison's disease in the differential diagnosis of unexplained hypertransaminasaemia.

Related Experiment Videos

  • This case underscores the importance of a comprehensive diagnostic approach for persistent, unexplained symptoms.