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Published on: April 13, 2015
Acute effects of nicotine content in cigarettes on coronary flow velocity and coronary flow reserve in men
1Department of Cardiology, Showa General Hospital, Kodaira-City, Tokyo, Japan.
Abstract:
We investigated the acute effects of smoking on coronary flow reserve in terms of the nicotine content of cigarettes in 21 smokers. Coronary flow velocity was measured with a Doppler flow wire. Subjects smoked cigarettes containing >1 mg nicotine (n = 8, group 1) or <1 mg (n = 6, group 2). Subjects in the control group mimicked smoking without a cigarette (n = 7). Coronary flow reserve decreased after smoking in group 1, but not in group 2 or the control group. This reduction may have mediated nicotine or some other unknown substances influenced by smoking.
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