[Hepatitis B vaccination strategies]
Related Experiment Video
Updated: Oct 27, 2026

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021
R Kammerlander1, H Zimmermann, B Vaudaux
1Abteilung Epidemiologie und Infektionskrankheiten, Bundesamt für Gesundheit, Bern.
Abstract:
With the introduction of a vaccine against hepatitis B in the early 1980s, a vaccination strategy targeted at high risk groups was implemented in most developed countries. Although such a strategy is efficient on an individual basis, it has been shown that it only has a limited impact on the overall rate of infections in the population. Public health authorities were therefore prompted to additionally recommend a universal vaccination strategy to reduce and ultimately eliminate hepatitis B infections. The option to primarily vaccinate infants, adolescents or both age groups depends on the epidemiological situation of a country, the availability of organisational facilities, financial resources and acceptability. Combining a targeted and a universal vaccination strategy provides the optimal protection against hepatitis B, both at an individual and population level.
Related Concept Videos
Hepatitis
Smallpox
Viral Hepatitis I: Introduction
Vaccinations
Vaccines
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
