Related Experiment Video
Updated: Jul 28, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Prepregnant weight and weight gain during pregnancy: relationship to functional status, symptoms, and energy
L Tulman1, K H Morin, J Fawcett
1University of Pennsylvania, School of Nursing, Philadelphia 19104-6096, USA.
Objective:
To examine the relationship of prepregnancy weight and pregnancy weight gain to functional status, physical symptoms, and physical energy.
Design:
Longitudinal panel, with data collected at the end of each trimester. Functional status was measured by the Inventory of Functional Status-Antepartum Period; physical symptoms, by the Symptoms Checklist; and physical energy, by a one-item question. Self-reported weight and height were used to calculate body mass index (BMI), using the formula weight[kg]/height[m2].
Setting:
Women's homes.
Participants:
Two hundred twenty-two women, whose pregnancies were low-risk, drawn from a larger study.
Results:
Women were classified by prepregnancy BMI as underweight (BMI < 19.8), normal weight (BMI = 19.8-26.0), or overweight (BMI > 26.0). The groups did not differ in weight gain by trimester, for an average total weight gain of 30.56 lb (SD = 10.18, range = 1-64) (p > .05), with overweight women therefore gaining less weight on a percentage basis (M = 16.87%) than women who were of normal weight (M = 23.58%) or were underweight (M = 26.02%) (p < .00005). The groups did not differ in functional status, physical energy, or number or type of physical symptoms. Women who gained more than the recommended amount of weight for their prepregnant weight group had a lower level of 3rd trimester functional status than those who did not.
Conclusions:
Individual counseling of women regarding food intake and excessive weight gain during pregnancy needs to be reconsidered in light of these findings.
Related Concept Videos
Teratogenicity
Obesity
Diabetes Mellitus: Type 2 and Gestational
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...

