Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Methicillin-resistant Staphylococcus aureus and Acinetobacter baumannii: an unexpected difference in epidemiologic

A T Bernards¹, H M Frénay, B T Lim

¹Department of Medical Microbiology, Leiden University Medical Centre, Leiden, The Netherlands.

American Journal of Infection Control

|December 4, 1998

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ceftazidime-avibactam resistance and restoration of carbapenem susceptibility in KPC-producing Klebsiella pneumoniae infections: A case series.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy·2021

Same author

RESIST-5 O.O.K.N.V. and NG-Test Carba 5 assays for the rapid detection of carbapenemase-producing Enterobacterales from positive blood cultures: a comparative study.

The Journal of hospital infection·2020

Same author

Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD).

Critical care (London, England)·2018

Same author

Re: 'Development of diagnostic prediction tools for bacteraemia caused by 3rd generation cephalosporin-resistant Enterobacteriaceae in suspected bacterial infections' by Rottier, et al.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2018

Same author

International Committee on Systematics of Prokaryotes. Minutes of the meetings, 7, 8 and 9 July 2017, Valencia, Spain.

International journal of systematic and evolutionary microbiology·2018

Same author

MALDI-TOF/MS identification of species from the Acinetobacter baumannii (Ab) group revisited: inclusion of the novel A. seifertii and A. dijkshoorniae species.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2016

Strict isolation prevented methicillin-resistant Staphylococcus aureus (MRSA) spread, but multiresistant Acinetobacter spread occurred in two hospitals. Current guidelines for gram-negative organisms may be insufficient, necessitating airborne precautions.

Area of Science:

Infectious Diseases
Hospital Epidemiology
Microbiology

Background:

Dutch guidelines mandate strict isolation for patients transferred from abroad to prevent methicillin-resistant Staphylococcus aureus (MRSA) spread.
Three patients colonized with MRSA and multiresistant Acinetobacter were transferred to Dutch hospitals.
Acinetobacter spread occurred in two of three hospitals despite isolation, while MRSA did not spread.

Observation:

Despite isolation, Acinetobacter spread in two hospitals, while MRSA did not spread in any.
The hospital with no Acinetobacter outbreak implemented airborne transmission precautions.

Findings:

Standard isolation measures, effective against MRSA, were insufficient to prevent Acinetobacter spread.
Epidemiologically related Acinetobacter isolates were indistinguishable from the index strains, indicating successful transmission.

Related Experiment Videos

Implications:

Current guidelines for multiresistant gram-negative organisms may be inadequate for Acinetobacter.
Airborne transmission of Acinetobacter must be considered in hospital infection control strategies.
Hospital isolation guidelines require revision to include airborne precautions for Acinetobacter.