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Effects of neocortical ectopias upon the acquisition and retention of a non-spatial reference memory task in BXSB
S A Balogh1, G F Sherman, L A Hyde
1Biobehavioral Sciences Graduate Degree Program, University of Connecticut, Storrs, CT 06269-4154, USA.
Brain Research. Developmental Brain Research
|December 5, 1998
Abstract:
BXSB mice have a 40-60% incidence of small, focal, neocortical dysplasias called ectopias. Ectopics and non-ectopics were compared on horizontal-vertical discrimination learning, a non-spatial cognitive task. No differences were found during acquisition. Ectopic mice, however, were superior when retested 8 weeks later. The results support prior findings that ectopic mice have better long-term spatial memory and extend this conclusion to the non-spatial domain.