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Development of a macromolecular prodrug of FK506: I. Synthesis of FK506-dextran conjugate

H Yura1, N Yoshimura, T Hamashima

  • 1Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.

Transplantation Proceedings
|December 5, 1998
PubMed
Abstract

No abstract available in PubMed .

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Prodrugs01:30

Prodrugs

Prodrugs are a class of pharmaceutical compounds that undergo a biotransformation process within the body to be converted into a pharmacologically active drug. Prodrugs are designed to improve the therapeutic properties of the parent drug, such as enhancing bioavailability, increasing stability, or reducing toxicity. The concept of prodrugs revolves around modifying the chemical structure of the original drug to make it more effective or convenient for administration.
Prodrugs help overcome...