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Related Experiment Videos

Group B streptococcal bacteraemia in the elderly

C Trivalle1, E Martin, P Martel

  • 1Service de Médecine Gériatrique, Centre Hospitalier et Universitaire de Rouen, France.

Journal of Medical Microbiology
|December 5, 1998
PubMed
Summary
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Group B Streptococcus (GBS) bacteraemia is a severe issue in older adults, often presenting as urinary tract infections. Being bedridden significantly increases mortality risk in elderly patients with GBS bacteraemia.

Area of Science:

  • Infectious Diseases
  • Geriatrics
  • Clinical Microbiology

Background:

  • Group B Streptococcus (GBS) is a significant pathogen, particularly in neonates, but also causes invasive disease in adults.
  • Understanding the clinical presentation and risk factors for GBS bacteraemia in the elderly is crucial for improving outcomes.

Purpose of the Study:

  • To investigate the clinical spectrum of GBS bacteraemia in patients aged 70 years and older.
  • To compare disease characteristics, diagnoses, and underlying conditions in elderly versus younger GBS bacteraemia patients.
  • To identify factors associated with GBS bacteraemia and mortality in older adults.

Main Methods:

  • Retrospective review of 66 adult patients with GBS bacteraemia over a 5-year period.
  • Comparison of 33 older patients (≥70 years) with 33 younger patients.

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  • Comparison of older GBS bacteraemia patients with an age-matched control group.

    • Main Results:

    • Urinary tract infection was the most frequent diagnosis in older patients (39%), significantly more common than in younger patients (6%).
    • Congestive heart failure (39%) and being bedridden (36%) were more frequent underlying conditions in the elderly.
    • Being bedridden was strongly associated with GBS bacteraemia and was a significant mortality factor in older patients (30% mortality vs. 10% in controls).

    Conclusions:

    • GBS bacteraemia in the elderly is a severe clinical problem with high mortality, even with appropriate treatment.
    • Urinary tract infections and conditions like congestive heart failure and immobility are key features in elderly GBS bacteraemia.
    • Immobility is a critical factor influencing outcomes and mortality in older adults with GBS bacteraemia.