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Related Experiment Videos

Left ventricular function by echocardiography in children with fixed aortic stenosis

G L Johnson, R A Meyer, D C Schwartz

    The American Journal of Cardiology
    |November 4, 1976
    PubMed
    Summary

    Echocardiography effectively assesses fixed aortic stenosis in children. The shortening fraction, a key metric, correlates with obstruction severity and surgical outcomes, offering a noninvasive evaluation method.

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    Area of Science:

    • Pediatric Cardiology
    • Cardiovascular Imaging
    • Congenital Heart Disease

    Background:

    • Fixed aortic stenosis is a significant congenital heart defect in children.
    • Accurate assessment of left ventricular function is crucial for managing aortic stenosis.
    • Noninvasive methods are preferred for evaluating pediatric cardiac conditions.

    Purpose of the Study:

    • To evaluate left ventricular function in children with fixed aortic stenosis using echocardiography.
    • To determine the utility of echocardiographic parameters in assessing stenosis severity and surgical response.
    • To establish the shortening fraction as a reliable noninvasive marker.

    Main Methods:

    • Echocardiography performed within 24 hours of cardiac catheterization in 45 children.

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  • Assessment of left ventricular systolic time intervals, mean velocity of circumferential fiber shortening, end-diastolic volume, and shortening fraction.
  • Comparison of findings with normal subjects and correlation with left ventricular-aortic gradient.

    • Main Results:

    • Severe aortic stenosis showed some altered systolic time intervals and increased mean velocity of circumferential fiber shortening, but inconsistently.
    • Left ventricular end-diastolic volume was reduced in severe stenosis.
    • Shortening fraction effectively differentiated significant from mild obstruction and correlated linearly with the left ventricular-aortic gradient.
    • Shortening fraction also predicted response to surgical relief.

    Conclusions:

    • Echocardiographic shortening fraction is a valuable noninvasive tool for assessing fixed aortic stenosis severity in children.
    • It aids in monitoring disease progression and evaluating surgical outcomes.
    • This method provides readily available, reliable data for clinical decision-making.