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Haemophilus paraphrophilus endocarditis in a prolapsed mitral valve
American Journal of Clinical Pathology
|November 1, 1976
Summary
This case study details successful ampicillin treatment for Haemophilus paraphrophilus endocarditis in a patient with a prolapsed mitral valve. Accurate identification of H. paraphrophilus is crucial for effective treatment.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Endocarditis is a serious infection of the heart lining or valves.
- Prolapsed mitral valves are a known risk factor for infective endocarditis.
- Haemophilus species are increasingly recognized as causes of endocarditis.
Observation:
- A 24-year-old woman with a prolapsed mitral valve presented with endocarditis.
- The causative organism, Haemophilus paraphrophilus, was initially misidentified as Haemophilus parainfluenzae.
- Distinguishing features of H. paraphrophilus include a 10% CO2 requirement for growth and inability to ferment xylose.
Findings:
- Successful treatment of Haemophilus paraphrophilus endocarditis was achieved with ampicillin.
- The case highlights the importance of accurate microbiological identification for appropriate therapy.
Implications:
- This case underscores the potential for Haemophilus species, particularly H. paraphrophilus, to cause endocarditis.
- Prompt and correct diagnosis, guided by specific growth requirements and biochemical tests, is essential for successful management of H. paraphrophilus endocarditis.
- Ampicillin can be an effective treatment option for this specific type of endocarditis.