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Related Experiment Videos

Preoperative magnesium trisilicate in infants

B R Hutchinson

    Anaesthesia and Intensive Care
    |August 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Magnesium trisilicate effectively reduces gastric acidity in young children before surgery. This antacid medication helps ensure a safer anesthetic procedure by lowering the risk of acid reflux.

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    Area of Science:

    • Pediatric Anesthesiology
    • Gastrointestinal Physiology

    Background:

    • High gastric acidity in pediatric patients poses an aspiration risk during anesthesia.
    • Preoperative fasting alone may not sufficiently reduce gastric acidity.

    Purpose of the Study:

    • To evaluate the efficacy of magnesium trisilicate in neutralizing gastric acidity in children under five years old before elective surgery.

    Main Methods:

    • Three groups of forty children (<5 years) undergoing elective surgery were studied.
    • Gastric volume and pH were measured.
    • Magnesium trisilicate was administered 30 minutes prior to anesthesia induction in two groups.

    Main Results:

    • The control group exhibited high gastric acidity (pH ≤ 2.5) in 67.5% of cases.

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  • Administration of magnesium trisilicate significantly reduced gastric acidity post-induction.
  • Gastric acid neutralization remained effective at the termination of anesthesia and surgery in most cases.

    • Conclusions:

    • Magnesium trisilicate is an effective agent for reducing gastric acidity in pediatric surgical patients.
    • This intervention can potentially mitigate the risk of aspiration pneumonitis.
    • Further research into optimal dosing and timing may be warranted.