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Sweet's syndrome associated with systemic inflammatory response syndrome

P C Matthews¹, S M Willatts

¹Department of Anaesthesia and Intensive Care, Bristol Royal Infirmary, UK.

Intensive Care Medicine

|December 5, 1998

Summary

Septic shock, a severe infection response, can be linked to Sweet's syndrome. Early steroid treatment for this rare association rapidly improved patient outcomes.

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Area of Science:

Infectious Diseases
Dermatology
Critical Care Medicine

Background:

Septic shock involves systemic inflammation and circulatory collapse, typically treated with antibiotics and supportive care.
Pyelonephritis is a common cause of infection leading to septic shock.
Conventional treatments may fail in complex or atypical cases of septic shock.

Observation:

A patient with presumed pyelonephritis-induced septic shock showed persistent deterioration despite standard care.
The patient's condition unexpectedly improved after the diagnosis of Sweet's syndrome.
Sweet's syndrome, an uncommon neutrophilic dermatosis, was identified as a potential underlying cause.

Findings:

This case presents a severe systemic inflammatory response syndrome (SIRS) associated with Sweet's syndrome.
High-dose steroid therapy was effective in managing the patient's condition.
The successful treatment highlights an unusual but treatable cause of septic shock.

Implications:

This case suggests a potential link between Sweet's syndrome and severe systemic inflammatory response syndrome.
It underscores the importance of considering rare diagnoses in refractory septic shock cases.
Early recognition and steroid treatment may be crucial for patients with this specific association.

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