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Dedifferentiated parosteal osteosarcoma with high-grade osteoclast-rich osteogenic sarcoma at presentation
1Department of Pathology, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada.
Skeletal Radiology
|December 5, 1998
Abstract:
We report a case of a 32-year-old woman who presented with parosteal osteosarcoma of the distal femur with simultaneous dedifferentiation to a high-grade osteoclast-rich osteogenic sarcoma. This pattern of dedifferentiation is rare, particularly at the time of presentation. We are aware of three other somewhat comparable cases in the literature; however, none is quite similar to our case.