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Related Experiment Videos

Oculomotor dysfunction in rheumatoid patients with upper cervical dislocation

B I Wenngren1, G Toolanen, C Hildingsson

  • 1Department of Otorhinolaryngology, University of Umeå, Sweden.

Acta Oto-Laryngologica
|December 5, 1998
PubMed
Summary
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Rheumatoid arthritis patients with upper cervical dislocation often experience eye movement problems, suggesting potential brainstem involvement. These oculomotor disturbances may signal early myelopathy in rheumatoid arthritis patients.

Area of Science:

  • Neurology
  • Rheumatology
  • Ophthalmology

Background:

  • Chronic cervical pain and whiplash syndrome are linked to oculomotor dysfunction, suggesting brainstem or neck afferent sensory input issues.
  • Upper cervical spine disorders in rheumatoid arthritis (RA) warrant investigation for similar oculomotor impairments.

Purpose of the Study:

  • To evaluate voluntary eye motor performance in RA patients with upper cervical dislocation.
  • To compare oculomotor function between RA patients with and without cervical spine involvement and healthy individuals.

Main Methods:

  • Assessed voluntary eye motor performance in 11 RA patients with upper cervical dislocation.
  • Compared findings with 6 RA patients without cervical engagement and a control group of normal individuals.

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Main Results:

  • Nine out of eleven RA patients with atlanto-axial dislocation exhibited significant smooth pursuit oculomotor disturbances.
  • Minor oculomotor changes were observed in the control group, highlighting a distinct pattern in the affected RA patients.

Conclusions:

  • Oculomotor dysfunction in RA patients with cervical dislocation suggests brainstem involvement.
  • This dysfunction may serve as an early indicator of brainstem affection or myelopathy in rheumatoid arthritis.