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[Probiotics in childhood]

G D'Angelo1, C Angeletti, C Catassi

  • 1Istituto di Clinica Pediatrica, Università degli Studi, Ancona.

Minerva Pediatrica
|December 8, 1998
PubMed
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Probiotics, or lactic acid bacteria, are live microbial supplements that improve gut health. They show promise in treating diarrhea and inflammatory conditions by modulating immune responses.

Area of Science:

  • Microbiology and Immunology
  • Gastroenterology

Context:

  • Probiotics, specifically Lactic Acid Bacteria, are live microbial supplements.
  • These supplements positively influence host health by enhancing microbial balance.

Purpose:

  • To review studies on probiotics for preventing and treating various diarrheal diseases.
  • To explore the potential of probiotics in managing inflammatory and immune-related conditions.

Summary:

  • Probiotics are investigated for infantile acute diarrhea, pseudomembranous colitis, and hospital-acquired/antibiotic-associated diarrheas.
  • Their mechanism involves immune response modulation and inhibition of intestinal inflammation.
  • Suggested applications include inflammatory bowel diseases, rheumatoid arthritis, food allergies, and atopic dermatitis.

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Impact:

  • Probiotics offer a potential therapeutic strategy for gastrointestinal disorders.
  • They may play a role in managing immune-mediated diseases.
  • Further research into their immunomodulatory effects could expand their clinical use.