Inflammatory pseudotumor of the pelvis: case report with review of recent developments
1Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Abstract:
A case of a successfully treated inflammatory pseudotumor (IPT) of the pelvis in a 9-year-old male is presented. Review of the literature indicates that IPTs have been reported from a variety of anatomic locations. They form a spectrum of lesions ranging from benign, infection-related lesions to low-grade malignancies, capable of local recurrences and rare distant metastases. The site of involvement seems to have prognostic implication. Pulmonary IPTs are found in older patients and are almost always benign, whereas extrapulmonary IPTs tend to occur in younger patients and are, in general, more aggressive, with a recurrence rate of up to 24 per cent and mortality of up to 7 per cent. The treatment of choice is complete resection of the lesion.
Insights
A pediatric pelvic inflammatory pseudotumor (IPT) was successfully treated. This rare tumor spectrum ranges from benign to malignant, with extrapulmonary IPTs in younger patients being more aggressive.
Area of Science:
- Oncology
- Pathology
Background:
- Inflammatory pseudotumors (IPTs) are a diverse group of lesions.
- IPTs can occur in various anatomical locations, presenting a diagnostic challenge.
Observation:
- A case of a successfully treated pelvic inflammatory pseudotumor in a 9-year-old male is presented.
- Literature review indicates IPTs span a spectrum from benign to low-grade malignant.
Findings:
- Extrapulmonary IPTs, often seen in younger patients, demonstrate increased aggressiveness compared to pulmonary counterparts.
- Recurrence rates for extrapulmonary IPTs can reach 24%, with a mortality rate of up to 7%.
Implications:
- The anatomical site of IPT involvement significantly impacts prognosis.
- Complete surgical resection remains the primary treatment modality for inflammatory pseudotumors.
