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Mitomycin, ifosfamide and cisplatin in advanced non-small cell lung cancer
Singapore Medical Journal
|December 9, 1998
Abstract
Background:
Chemotherapy can be used to palliate the symptoms in patients with advanced non-small cell lung cancer.
Patients:
Twenty-four chemo-naive patients with stage IIIB and IV non-small cell lung cancer were treated with the MIC regimen (mitomycin, ifosfamide and cisplatin).
Results:
The overall response rate was 33% (partial response) and median duration of response was 7 months (range 5 to 10 months). At median follow-up of 26 months, the median survival was 8 months, and 1-year survival was 29%. Toxicities were tolerable.
Conclusion:
This appears to be a reasonable regimen for palliating advanced non-small cell lung cancer.