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[Yellow staphylococci with borderline resistance to methicillin]
S Gjeruldsen1, G Syversen, E von der Lippe
1Infeksjonsmedisinsk avdeling, Ullevål sykehus, Oslo.
Summary
Borderline-resistant Staphylococcus aureus infections are increasing, particularly hospital-acquired cases in Norway. This study examines clinical outcomes and risk factors for these serious Staphylococcus aureus infections.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Context:
- An increasing incidence of borderline-resistant Staphylococcus aureus (S. aureus) has been observed at Ullevål University Hospital.
- Severe infections caused by these S. aureus strains have been noted in the hospital's Infectious Diseases department.
Purpose:
- To examine the clinical and microbiological outcomes of patients with borderline-resistant S. aureus infections.
- To discuss the etiology, risk factors, and management strategies for these infections.
Summary:
- A study of 24 patients from December 1994 to April 1997 revealed that 15 had hospital-acquired infections, mostly in Norway.
- Predisposing factors were present in 13 patients, with 50% having prior antibiotic use (primarily cefalosporins).
- Three out of 24 patients succumbed to the infection.
Impact:
- Highlights the growing threat of resistant S. aureus in healthcare settings.
- Informs identification of at-risk populations and guides clinical management protocols.
- Contributes to understanding the epidemiology and outcomes of emerging antibiotic resistance.