Arizona hinshawii infections. New cases, antimicrobial sensitivities, and literature review
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Updated: Jan 10, 2026
Disorders of Erythrocytes
Abstract:
Although disease caused by Arizona hinshawii is known to resemble the spectrum of clinical syndromes seen with Salmonella infections, little is known of their sensitivity to antimicrobials. We present three cases that are illustrative of Arizona sepsis, localized infection, or both; review the literature; and report sensitivities to 12 antimicrobials for 32 human and animal isolates of Arizona hinshawii from various geographic areas. With the exception of erythromycin and streptomycin, most strains were sensitive to many of the commonly used antibiotics. As with Salmonella infections, ampicillin or chloramphenicol appear to be the initial antimicrobial agents of choice for severe infections with A. hinshawii. Definitive antimicrobial therapy must be individualized on the basis of sensitivity testing and with regard to host factors.
Insights
Arizona hinshawii infections, similar to Salmonella, show varied antimicrobial sensitivity. Most strains are susceptible to common antibiotics, with ampicillin or chloramphenicol recommended for severe cases.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Arizona hinshawii infections present clinical syndromes similar to Salmonella.
- Limited data exists regarding the antimicrobial susceptibility of Arizona hinshawii.
Observation:
- Three cases of Arizona hinshawii infection (sepsis, localized infection) were analyzed.
- Literature review and antimicrobial sensitivity testing of 32 human and animal isolates were conducted.
Findings:
- Most Arizona hinshawii strains demonstrated sensitivity to commonly used antibiotics, excluding erythromycin and streptomycin.
- Ampicillin and chloramphenicol are suggested as initial choices for severe Arizona hinshawii infections, akin to Salmonella.
Implications:
- Individualized antimicrobial therapy based on sensitivity testing is crucial for Arizona hinshawii infections.
- Understanding antimicrobial profiles aids in effective treatment strategies for these infections.
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