Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tracheal afferent nerves

R M Traxel, W F Prudlow, J P Kampine

    The Annals of Otology, Rhinology, and Laryngology
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Subtype composition and responses of respiratory neurons in the pre-botzinger region to pulmonary afferent inputs in dogs.

    Journal of neurophysiology·2004
    Same author

    Laser revascularization of ischemic skeletal muscle.

    The Journal of surgical research·2003
    Same author

    Differential processing of excitation by GABAergic gain modulation in canine caudal ventral respiratory group neurons.

    Journal of neurophysiology·2003
    Same author

    Differential modulation of respiratory neuronal discharge patterns by GABA(A) receptor and apamin-sensitive K(+) channel antagonism.

    Journal of neurophysiology·2001
    Same author

    David Waritier: recipient of the 2001 Excellence in Research Award.

    Anesthesiology·2001
    Same author

    Effects of sevoflurane on excitatory neurotransmission to medullary expiratory neurons and on phrenic nerve activity in a decerebrate dog model.

    Anesthesiology·2001
    Same journal

    Laryngeal Injuries Following General Endotracheal Anesthesia: A Case Series.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Clinical and Voice Outcome Differences in Vocal Cord Cysts with and Without Sulcus Vocalis: Insights From a Tertiary Center in Saudi Arabia.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Bioabsorbable Stenting in a Case of Severe Pediatric Posterior Glottic Stenosis.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Efficacy and Safety of Finafloxacin Otic Suspension, 0.3% for the Treatment of Acute Otitis Externa: Results from two Phase III Randomized Clinical Studies.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Evaluation Of the Expression Levels Of SerpinB3/B4/B10, Interleukin-17 As Biomarkers For Chronic Rhinosinusitis With Nasal Polyps.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Correlation of Patient-Reported Symptoms With Rhinogram Features Beyond Simple Airway Resistance.

    The Annals of otology, rhinology, and laryngology·2026
    See all related articles

    Researchers studied upper airway mechano-receptors in dogs. These receptors, located in the trachea, influence breathing and protective reflexes, impacting respiration and blood pressure regulation.

    Area of Science:

    • Neuroscience
    • Respiratory Physiology

    Background:

    • The role of upper airway mechano-receptors in respiratory control is not fully understood.
    • The inferior laryngeal nerve and superior laryngeal nerve innervate the upper trachea.

    Purpose of the Study:

    • To investigate the afferent nerve activity of upper airway mechano-receptors.
    • To determine the reflex effects of stimulating these nerve fibers.

    Main Methods:

    • Studied nerve activity from the inferior laryngeal nerve and superior laryngeal nerve in 30 mongrel dogs.
    • Utilized intact and isolated tracheal segments with artificial pressure and flow stimuli.
    • Recorded adaptation rate, threshold, and firing frequencies of afferent nerve discharge.
    • Electrically stimulated nerve fibers to observe reflex responses.

    Related Experiment Videos

    Main Results:

    • Upper tracheal afferent nerve activity responded to pressure changes from 0.5 to 12 mm Hg.
    • Nerve activity frequency correlated with the frequency of pressure changes.
    • Electrical stimulation induced reflex bradycardia, bradypnea, and altered blood pressure.

    Conclusions:

    • Upper airway mechano-receptors are sensitive to tracheal pressure and flow.
    • These receptors play a role in initiating protective airway reflexes.
    • Mechano-receptors contribute to the regulation of normal respiration.