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5S Ribosomal RNA Data Bank

M Szymanski1, M Z Barciszewska, J Barciszewski

  • 1Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Noskowskiego 12, 61704 Poznan, Poland.

Nucleic Acids Research
|December 10, 1998
PubMed
Summary

This updated database provides 1889 ribosomal 5S ribonucleic acid (5S rRNA) and 5S ribosomal DNA (5S rDNA) sequences. It offers a comprehensive resource for studying these crucial genetic elements across diverse organisms.

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Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Ribosomal 5S RNA (5S rRNA) and its genes (5S rDNA) are essential components of ribosomes.
  • Understanding the diversity and evolution of 5S rRNA and 5S rDNA sequences is crucial for molecular biology and genomics.
  • Existing databases require regular updates to incorporate new sequence data.

Purpose of the Study:

  • To present an updated version of the 5S rRNA and 5S rDNA database.
  • To provide a comprehensive and accessible resource for researchers studying 5S rRNA and 5S rDNA.
  • To facilitate the retrieval and analysis of these sequences based on taxonomic classification.

Main Methods:

  • Compilation and curation of publicly available 5S rRNA and 5S rDNA sequences.
  • Database management and organization based on taxonomic groups.
  • Development of a web-based taxonomic browser for data retrieval.

Main Results:

  • The updated database contains 1889 primary structures of 5S rRNA and 5S rDNA.
  • Sequences are categorized into Archaebacterial (60), Eubacterial (439), Plastid (63), Mitochondrial (9), and Eukaryotic (1318).
  • A user-friendly taxonomic browser is available at http://rose.man.poznan.pl/5SData/5SRNA.html for data access.

Conclusions:

  • The updated 5S rRNA and 5S rDNA database serves as a valuable resource for evolutionary and functional studies.
  • The comprehensive collection and taxonomic organization aid in comparative sequence analysis.
  • Easy accessibility through the provided URL promotes wider research utilization.

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