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Updated: Aug 2, 2026
09:16
Eukaryotic Polyribosome Profile Analysis
Published on: June 16, 2010
A new version of the RDP (Ribosomal Database Project)
B L Maidak1, J R Cole, C T Parker
1Department of Microbiology, Michigan State University, 294 Giltner Hall, East Lansing, MI 48824-1101, USA.
Nucleic Acids Research
|December 10, 1998
Summary
The Ribosomal Database Project (RDP-II) offers updated ribosomal RNA (rRNA) sequence data and analysis tools. This enhanced database improves data accuracy and user access for microbial ecology research.
Area of Science:
- Microbial Ecology
- Bioinformatics
- Molecular Biology
Background:
- The Ribosomal Database Project (RDP-II) is a vital resource for ribosomal RNA (rRNA) sequence data.
- Previous versions have provided essential tools for microbial community analysis.
- The database requires continuous updates to incorporate new sequence data and enhance functionality.
Purpose of the Study:
- To announce the relocation and enhanced capabilities of the Ribosomal Database Project (RDP-II).
- To highlight updates in data volume, accuracy, and accessibility.
- To showcase new analysis services and software utilities for rRNA data.
Main Methods:
- Curated collection and alignment of >9700 small subunit rRNA sequences.
- Implementation of an ObjectStore database for improved data management.
- Development of web-based services including probe checking and phylogenetic placement.
Main Results:
- Updated alignments now include over 9700 small subunit rRNA sequences.
- ObjectStore database enhances data updating speed, accuracy, and user access.
- Web server offers advanced tools like chimeric sequence screening and automated alignment.
Conclusions:
- RDP-II continues to be a leading resource for microbial rRNA data analysis.
- Enhanced features facilitate more efficient and accurate phylogenetic and ecological studies.
- The project's ongoing development ensures its relevance for the scientific community.
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