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Database on the structure of large subunit ribosomal RNA
P De Rijk1, E Robbrecht, S de Hoog
1Departement Biochemie, Universiteit Antwerpen (UIA), Universiteitsplein 1, B-2610 Antwerpen, Belgium.
Nucleic Acids Research
|December 10, 1998
Summary
The Antwerp database now houses 607 aligned ribosomal RNA sequences, incorporating secondary structure details. This valuable resource for molecular biology research is accessible online.
Area of Science:
- Molecular Biology
- Bioinformatics
- Genomics
Background:
- Ribosomal RNA (rRNA) is crucial for protein synthesis and serves as a phylogenetic marker.
- Databases of aligned rRNA sequences are essential for comparative analysis and evolutionary studies.
Purpose of the Study:
- To present an updated version of the Antwerp database for large subunit ribosomal RNA (rRNA).
- To provide a comprehensive resource for researchers studying rRNA sequences and their structures.
Main Methods:
- Compilation of 607 complete or nearly complete large subunit rRNA sequences.
- Alignment of sequences incorporating secondary structure information.
- Integration of associated data including literature references, accession numbers, and taxonomic details.
Main Results:
- The database now contains 607 aligned large subunit rRNA sequences.
- Secondary structure information is integrated into the alignment.
- Comprehensive metadata is available for each sequence.
Conclusions:
- The Antwerp database is a valuable and updated resource for researchers in molecular evolution and bioinformatics.
- The integrated secondary structure information enhances the utility of the rRNA sequence data.
- Online accessibility facilitates data retrieval and analysis for the scientific community.