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Current status of the Asthma and Allergy Database
1GSF National Research Center for Environment and Health, Institute of Epidemiology, PO Box 1129, D-85758 Neuherberg, Germany.
Nucleic Acids Research
|December 10, 1998
Summary
This database offers genetic data for asthma and allergy research, detailing linkage and mutation studies. It serves as a valuable online resource for scientists studying these conditions.
Area of Science:
- Genetics
- Bioinformatics
- Immunology
Background:
- Asthma and allergy are complex conditions with significant genetic components.
- Understanding the genetic basis is crucial for developing effective treatments.
- Existing data resources require consolidation and improved accessibility.
Purpose of the Study:
- To present the current status and content of an online database for asthma and allergy genetics.
- To provide researchers with a centralized resource for genetic study data.
- To facilitate the discovery of genes and mutations associated with asthma and allergy.
Main Methods:
- Compilation of data from 88 linkage studies and 72 mutation studies.
- Inclusion of mouse asthma models and human homology data.
- Development of a user-friendly interface for data access and visualization.
Main Results:
- The database currently details 88 linkage studies (7164 positions) and 72 mutation studies.
- Results are accessible via tables and graphical representations.
- Includes data on mouse asthma studies, human homology, gene expression, and patents.
Conclusions:
- The database serves as a comprehensive online resource for asthma and allergy genetics.
- It supports genetic research by providing structured access to diverse study data.
- Facilitates further investigation into the genetic underpinnings of asthma and allergy.
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