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The SWISS-2DPAGE database: what has changed during the last year
C Hoogland1, J C Sanchez, L Tonella
1Swiss Institute of Bioinformatics, c/o Medical Informatics Division, Geneva University Hospital, 24 rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. christine.hoogland@isb-sib.ch
Nucleic Acids Research
|December 10, 1998
Summary
The SWISS-2DPAGE database, a key resource for two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) data, has been updated with new reference maps and enhanced data access functions. This expansion improves its utility for proteomic research.
Area of Science:
- Proteomics
- Biochemistry
- Bioinformatics
Background:
- SWISS-2DPAGE is an established database for two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) data, initiated in 1993.
- It provides reference maps for various organisms, including human, mouse, Saccharomyces cerevisiae, Escherichia coli, and Dictyostelium discoideum.
Purpose of the Study:
- To report on the recent updates and enhancements to the SWISS-2DPAGE database.
- To highlight the expanded content and improved data accessibility.
Main Methods:
- The database utilizes annotated two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) reference maps.
- Data integration with SWISS-PROT sequences for virtual entries.
Main Results:
- The current release features 21 reference maps with 2480 identified spots, representing 528 distinct protein entries.
- Six new maps have been added, and new data access functions are available via the ExPASy server.
- Changes in the database funding source were also noted.
Conclusions:
- SWISS-2DPAGE continues to be a valuable resource for the scientific community.
- Recent updates enhance its comprehensiveness and user accessibility for proteomic studies.