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PlantCARE, a plant cis-acting regulatory element database
S Rombauts1, P Déhais, M Van Montagu
1Laboratorium voor Genetica, Vlaams Interuniversitair Instituut voor Biotechnologie (VIB), Universiteit Gent,K.L. Ledeganckstraat 35, B-9000 Gent, Belgium.
Nucleic Acids Research
|December 10, 1998
Summary
PlantCARE is a comprehensive database detailing plant cis-acting regulatory elements, including enhancers and repressors. It links regulatory motifs to gene sequences and functional conditions, aiding plant molecular biology research.
Area of Science:
- Plant Molecular Biology
- Bioinformatics
- Genomics
Background:
- Understanding gene regulation is crucial for plant science.
- Databases for plant regulatory elements are essential tools for researchers.
Purpose of the Study:
- To introduce PlantCARE, a relational database for plant cis-acting regulatory elements.
- To provide a centralized resource for transcription motifs, gene sequences, and functional conditions.
Main Methods:
- Development of a relational database structure.
- Integration of data on plant cis-acting regulatory elements, including motifs, matrices, and consensus sequences.
- Linking regulatory information to EMBL entries for full gene sequences and functional contexts.
Main Results:
- PlantCARE provides access to plant cis-acting regulatory elements, enhancers, and repressors.
- The database links transcription motifs to specific gene sequences and their functional conditions.
- Information is presented using matrices, consensus, and individual site sequences.
Conclusions:
- PlantCARE serves as a valuable web-accessible resource for plant molecular biology.
- The database facilitates the study of gene regulation in plants by connecting regulatory elements to genomic and functional data.