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Object oriented Transcription Factors Database (ooTFD)

D Ghosh1

  • 1Institute for Transcriptional Informatics, PO Box 2556, Pittsburgh, PA 15230-2556, USA. dghosh@ifti.org

Nucleic Acids Research
|December 10, 1998
PubMed
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Transcription factors (TFs) are crucial for gene expression regulation. The ooTFD database, an object-oriented resource, has expanded with new tools for accessing and analyzing TF information, supporting genomics research.

Area of Science:

  • Bioinformatics
  • Molecular Biology
  • Genomics

Background:

  • Transcription factors (TFs) are proteins central to gene expression regulation.
  • The increasing volume of genome sequence data highlights the importance of TF information.
  • Understanding TFs is essential for 21st-century biology and genomics.

Purpose of the Study:

  • To describe the ooTFD database, an object-oriented resource for transcription factor information.
  • To report updates and new tools for data access and analysis.
  • To provide access to TF data and associated resources via the MIRAGE website.

Main Methods:

  • Development of an object-oriented database (ooTFD) for TF representation.
  • Implementation of new tools for data access and analysis.

Related Experiment Videos

  • Web-based resource provision at the MIRAGE website.

    • Main Results:

    • The ooTFD database has seen a modest size increase.
    • New tools have been added to facilitate data access and analysis.
    • The ooTFD database and associated resources are available online.

    Conclusions:

    • The ooTFD database serves as a valuable resource for transcription factor information.
    • Enhanced tools improve accessibility and utility for biological research.
    • The database supports the growing field of genomics and gene expression analysis.