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[Two cases of Achromobacter xylosoxidans sepsis]

A Kobayashi1, K Mori, M Konishi

  • 1Second Department of Internal Medicine, Nara Medical University.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
|December 16, 1998
PubMed

Insights

Achromobacter xylosoxidans bacteremia is rare in humans, particularly in immunocompromised patients. This study reports two cases in patients with hematologic malignancies, suggesting a link to catheters and neutropenia.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases

Background:

  • Achromobacter xylosoxidans is a Gram-negative bacterium found in diverse environments, including hospitals.
  • Human infections with A. xylosoxidans can lead to various conditions, but bacteremia is uncommon.
  • Limited data exists on the treatment of A. xylosoxidans bacteremia.

Observation:

  • Two cases of A. xylosoxidans bacteremia in patients with hematologic malignancies (plasmacytoma and acute lymphatic leukemia) are presented.
  • Both patients had indwelling catheters and presented with neutropenia (WBC counts of 20/microliter and 35/microliter).

Findings:

  • A. xylosoxidans bacteremia occurred in two immunocompromised patients.
  • The presence of catheters and neutropenia were noted in both cases.

Implications:

  • Catheter use and neutropenia may be risk factors for developing A. xylosoxidans bacteremia in susceptible individuals.
  • Further research is needed to understand the pathogenesis and optimal treatment strategies for A. xylosoxidans bacteremia.

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