[Mendelson syndrome in infancy and childhood]
1Klinik und Poliklinik für Kinderheilkunde der Martin-Luther-Universität Halle-Wittenberg.
Pneumologie (Stuttgart, Germany)
|December 16, 1998
Summary
Mendelson's syndrome, acute pulmonary failure from gastric acid aspiration, presents with bronchial obstruction, pulmonary edema, and right ventricular failure. Therapy follows intensive care standards for acute respiratory distress syndrome (ARDS).
Area of Science:
- Pulmonology
- Critical Care Medicine
Background:
- Mendelson's syndrome is acute pulmonary failure due to gastric acid aspiration.
- It classically presents with bronchial obstruction, pulmonary edema, and right ventricular failure.
Purpose of the Study:
- To describe the pathomorphological pulmonary alterations in Mendelson's syndrome.
- To correlate these alterations with clinical symptoms across three distinct phases.
Main Methods:
- Pathomorphological analysis of pulmonary alterations.
- Clinical classification based on three distinct phases of injury.
Main Results:
- Phase 1: Cauterization of bronchial and alveolar epithelium.
- Phase 2: Development of alveolar edema, impaired surfactant synthesis, and hyaline membrane formation.
- Phase 3: Proliferative fibrosis.
Conclusions:
- Pulmonary alterations in Mendelson's syndrome mirror those of acute respiratory distress syndrome (ARDS).
- The syndrome progresses through three distinct phases, each with characteristic clinical symptoms.
- Treatment is symptomatic, adhering to intensive care protocols for ARDS.
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