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Related Experiment Videos

Malacoplakia in a colonic adenoma: case report

H Chang1, C L Kwok

  • 1Department of Pathology, Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.

Changgeng Yi Xue Za Zhi
|December 16, 1998
PubMed
Summary

This study details a rare case of colonic malacoplakia found within a tubular adenoma. Careful histologic examination is crucial for diagnosing this uncommon condition, often associated with colorectal cancer.

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Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Colonic malacoplakia is a rare inflammatory condition.
  • It is often associated with other gastrointestinal diseases, particularly colorectal carcinoma.

Observation:

  • A 67-year-old male presented with a polypoid lesion in the left colon during a routine examination.
  • Histopathological analysis revealed a tubular adenoma with malacoplakia, characterized by histiocytes with Michaelis-Gutmann bodies.

Findings:

  • This case represents one of only three reported instances of colonic malacoplakia associated with an adenoma.
  • Literature review identified 35 documented cases of colonic malacoplakia.

Implications:

  • The association of colonic malacoplakia with adenoma is exceptionally rare.
  • This finding suggests colonic malacoplakia may be more prevalent than currently recognized.
  • Emphasizes the importance of thorough histologic examination for accurate diagnosis.

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