Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in plasma leptin during the menstrual cycle

M G Riad-Gabriel1, S D Jinagouda, A Sharma

  • 1Department of Medicine, University of Southern California Medical School, Los Angeles, USA.

European Journal of Endocrinology
|December 16, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression.

Journal of immunology (Baltimore, Md. : 1950)·1997
Same author

MR imaging of tubercular spinal arachnoiditis.

AJR. American journal of roentgenology·1997
Same author

Interactions between transvenous nonthoracotomy cardioverter defibrillator systems and permanent transvenous endocardial pacemakers.

Pacing and clinical electrophysiology : PACE·1997
Same author

Role of the carboxyl-terminal region of Porphyromonas gingivalis fimbrillin in binding to salivary proteins.

Infection and immunity·1997
Same author

Phenethyl isothiocyanate modulates clastogenicity of mitomycin C and cyclophosphamide in vivo.

Mutation research·1996
Same author

Expression of functional Porphyromonas gingivalis fimbrillin polypeptide domains on the surface of Streptococcus gordonii.

Applied and environmental microbiology·1996

Plasma leptin levels rise during the menstrual cycle in women, peaking in the luteal phase. This suggests leptin may play a role in reproductive function and preparing for pregnancy.

Area of Science:

  • Reproductive Endocrinology
  • Hormonal Regulation
  • Human Physiology

Background:

  • Leptin, a hormone produced by adipocytes, is expressed in ovarian follicles.
  • Leptin is hypothesized to play a role in reproductive functions.
  • Understanding hormonal fluctuations during the menstrual cycle is crucial for reproductive health.

Purpose of the Study:

  • To quantify plasma leptin concentrations throughout the menstrual cycle in healthy women.
  • To investigate the potential reproductive function of leptin.
  • To establish baseline leptin levels in control groups.

Main Methods:

  • Blood samples were collected every 1-2 days from nine women with regular menstrual cycles.
  • Plasma leptin levels were measured throughout the follicular and luteal phases.

Related Experiment Videos

  • Control measurements were taken in postmenopausal women and men.

    • Main Results:

    • Plasma leptin significantly increased from the early follicular phase to the midluteal phase in menstruating women.
    • Leptin levels returned to baseline by the next menses.
    • No significant changes in leptin were observed in postmenopausal women or men, and changes were not linked to sex hormones.

    Conclusions:

    • The observed increase in plasma leptin during the menstrual cycle suggests a potential role in reproductive regulation.
    • Possible causes include increased adipocyte production, hypothalamic neuropeptide Y, or release from ovarian follicles.
    • Leptin may prepare the body for metabolic demands of pregnancy.