Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Tuberous sclerosis: case report with histopathological and ultrastructural study]

J S Reis Filho1, M R Montemór Netto, J G Loyola Netto

  • 1Serviço de Anatomia Patológica (SAP), Hospital das Clínicas da Universidade Federal do Paraná (HC/UFPR), Curitiba PR, Brasil.

Arquivos De Neuro-Psiquiatria
|December 16, 1998
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association Between Renin-Angiotensin System Inhibitors and Antiseizure Medication Burden in Critically Ill Patients With Status Epilepticus.

The Annals of pharmacotherapy·2026
Same author

Entropy-based Model for Gully Erosion - A combination of probabilistic and deterministic components.

The Science of the total environment·2022
Same author

Comparative analysis of non-motor symptoms in patients with Parkinson's Disease and atypical parkinsonisms.

Clinical neurology and neurosurgery·2020
Same author

Green Tea Prevents NAFLD by Modulation of miR-34a and miR-194 Expression in a High-Fat Diet Mouse Model.

Oxidative medicine and cellular longevity·2019
Same author

Nitrogen removal in a shallow maturation pond with sludge accumulated during 10 years of operation in Brazil.

Water science and technology : a journal of the International Association on Water Pollution Research·2017
Same author

The management of prostatic obstructions by perineal prostatectomy.

The Urologic and cutaneous review·2010

Tuberous sclerosis complex (TSC) is a genetic disorder. This case report presents the first ultrastructural findings of TSC in Latin America, highlighting its association with West syndrome.

Area of Science:

  • Neurology
  • Genetics
  • Pathology

Background:

  • Tuberous sclerosis complex (TSC) is an autosomal disorder characterized by hamartomas affecting the central nervous system.
  • Phacomatosis, a group of neurocutaneous disorders, includes TSC and presents diagnostic challenges.

Observation:

  • A 2-year-old girl with West syndrome, unresponsive to standard treatments (vigabatrin, trileptal, clonazepan), underwent a left frontal lobectomy.
  • Histopathological and ultrastructural analyses were performed on the resected tissue.

Findings:

  • The findings were consistent with tuberous sclerosis complex.
  • This case provides the first ultrastructural evidence of TSC in the Latin American literature.

Implications:

Related Experiment Videos

  • These ultrastructural findings contribute to understanding TSC, a complex phacomatosis.
  • The case emphasizes the importance of recognizing West syndrome as a potential clinical presentation of TSC.