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Related Experiment Videos

CINEMA--a novel colour INteractive editor for multiple alignments

D J Parry-Smith1, A W Payne, A D Michie

  • 1Department of Discovery Biology, Pfizer Central Research, Sandwich, UK. DJParry-Smith@camdd.co.uk

Gene
|December 16, 1998
PubMed
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CINEMA is a novel Java-based editor for manipulating and generating multiple sequence alignments. This tool offers interactive client-side processing, revolutionizing user interaction with bioinformatics databases.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Sequence Analysis

Background:

  • Multiple sequence alignment is crucial for understanding protein function and evolution.
  • Existing tools often require complex installations or lack interactive features.
  • Web-based bioinformatics tools need to be accessible and user-friendly.

Purpose of the Study:

  • To introduce CINEMA, a new Java-based editor for multiple sequence alignment.
  • To provide a flexible and interactive platform for alignment manipulation and generation.
  • To enhance user interaction with online bioinformatics databases.

Main Methods:

  • Developed CINEMA as a Java applet for cross-platform compatibility.
  • Integrated CINEMA with existing internet alignment databases and local alignment tools.

Related Experiment Videos

  • Enabled client-side processing of alignments with server-side storage options.

    • Main Results:

    • CINEMA allows interactive, client-side manipulation of sequence alignments.
    • The tool is accessible as a standalone application and integrated into the PRINTS database.
    • It eliminates the need for users to install software for advanced alignment processing.

    Conclusions:

    • CINEMA revolutionizes user interaction with bioinformatics data by enabling visualization and manipulation.
    • The flexible, reusable object-oriented design promotes rapid development of extensions.
    • This approach sets a new standard for web-based bioinformatics tools, moving beyond simple data provision.