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Aortitis with antiphospholipid antibodies: CT and MR findings
1Department of Radiology, Centre Hospitalo-Universitaire Paris XIII, Hôpital Jean Verdier, Bondy, France.
Abstract:
Two cases of aortitis associated with the presence of antiphospholipid antibodies (APAs) are reported. Only CT and MR imaging were able to show these unusual form of aortitis preferentially affecting the outer aortic tunics. We conclude that aortitis could be a new manifestation of primary antiphospholipid syndrome (APS) and the initial pathological process before the development of aortic thrombosis, reported as a classical complication of APS.
Insights
Aortitis, an inflammation of the aorta, may be a new manifestation of antiphospholipid syndrome (APS). This condition, associated with antiphospholipid antibodies (APAs), may precede aortic thrombosis.
Area of Science:
- Cardiovascular Medicine
- Rheumatology
- Radiology
Background:
- Antiphospholipid syndrome (APS) is an autoimmune disorder associated with a risk of thrombosis.
- Aortitis, or inflammation of the aorta, is a less common manifestation of autoimmune diseases.
- The relationship between APS and aortitis requires further investigation.