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Related Experiment Videos

Circulatory arrest under hypothermic anesthesia using abdominal cavity cooling

M Fujiki1, K Misumi, H Sakamoto

  • 1Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, Japan.

The Journal of Veterinary Medical Science
|December 16, 1998
PubMed
Summary

This study explored hypothermic anesthesia using abdominal cavity cooling for open-heart surgery in beagles. The method showed potential for organ protection, with successful recovery linked to lung and myocardial protection.

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Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Veterinary Medicine

Background:

  • Systemic hypothermia is used in open-heart surgery to protect organs.
  • Novel cooling methods are investigated to improve organ protection and surgical outcomes.

Purpose of the Study:

  • To evaluate the efficacy of abdominal cavity cooling for inducing systemic hypothermia.
  • To assess the potential for circulatory arrest during open-heart surgery using this method.
  • To determine factors influencing recovery after hypothermic cardiac arrest.

Main Methods:

  • Eighteen beagles were cooled via abdominal cavity ice infusion to esophageal temperatures of 30°C and 20-23°C.
  • Left-heart bypass was established, followed by cardiac arrest induced by aortic root infusion of cooled solution.

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  • Continuous monitoring of electrocardiogram (ECG) and arterial blood pressure (ABP), with periodic blood gas and hematocrit analysis.

    • Main Results:

    • Successful induction of hypothermia and cardiac arrest was achieved in the canine model.
    • Eleven dogs recovered without complications, four were not extubated but breathed spontaneously, and three did not achieve heart beat reappearance.
    • Higher partial pressure of oxygen (PaO2) during resuscitation correlated with complete recovery.

    Conclusions:

    • Abdominal cavity cooling is a viable method for inducing hypothermia for open-heart surgery.
    • This technique shows promise for organ protection, particularly the myocardium and lungs.
    • Optimizing lung protection alongside myocardial protection may enhance successful recovery rates.