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[Basic substituted thieno(3,4-d)pyrimidine carboxylic acids: synthesis via ANRORC-reaction starting from
1Institut für Pharmazie, Universität Leipzig, Germany.
Die Pharmazie
|December 16, 1998
Abstract:
The synthesis of 7-cyan-thieno[3,2-d]-1,3-oxazine 7 is reported. Reaction of 7 with primary amines gives the thieno[3,4-d]pyrimidincarboxylic acids 14 in a unusual ring transformation. Several synthesized compounds were tested as antiallergic agents.