Outpatient deep vein thrombosis treatment models
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Updated: Oct 26, 2026

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Published on: May 24, 2024
1Department of Pharmacy, Burnaby Hospital, British Columbia, Canada.
Insights
Over 40% of deep vein thrombosis (DVT) patients can be safely treated at home using low-molecular-weight heparin. This outpatient approach avoids hospitalization and reduces healthcare costs.
Area of Science:
- Cardiology
- Vascular Medicine
- Health Services Research
Background:
- Deep vein thrombosis (DVT) affects approximately 9000 Canadian patients annually.
- Current standard treatment involves 5-10 days of inpatient intravenous unfractionated heparin therapy, incurring significant costs.
- A substantial proportion of uncomplicated DVT cases are suitable for outpatient management.
Purpose of the Study:
- To explore the feasibility and benefits of outpatient treatment for deep vein thrombosis (DVT).
- To identify core models for implementing successful outpatient DVT treatment programs.
- To reduce healthcare costs associated with DVT management.
Main Methods:
- Review of existing DVT treatment protocols and resource utilization.
- Identification and description of five core models for outpatient DVT management.
- Pilot implementation of a medical day care clinic model at Burnaby Hospital.
Main Results:
- Over 40% of uncomplicated DVT patients (3600 annually in Canada) can be safely treated as outpatients.
- Outpatient treatment with low-molecular-weight heparin offers a cost-effective alternative to hospitalization.
- Interim evaluation of the Burnaby Hospital pilot program demonstrated overwhelming success.
Conclusions:
- Outpatient management of deep vein thrombosis (DVT) is a safe and effective strategy.
- Implementation of structured outpatient DVT programs can optimize resource use and reduce healthcare expenditures.
- Five distinct models exist to facilitate the adoption of outpatient DVT treatment across various healthcare settings.
Abstract:
Approximately 9000 patients are admitted annually to Canadian hospitals with a primary diagnosis of deep vein thrombosis (DVT). Although this is a serious medical condition, potentially more than 40% of all patients with uncomplicated DVT, or 3600 Canadian patients/year, may be safely treated as outpatients with low-molecular-weight heparin. Outpatient treatment avoids costly hospitalization that is required for the standard 5-10 days of intravenous unfractionated heparin therapy. Although institutions vary widely in the available resources, five core models can assist with successful implementation of an outpatient DVT treatment program while providing optimum use of each site's resources and clinical expertise. These models are as follows: anticoagulation clinic (thromboembolic clinic-service), medical day care clinic, emergency department fast-track, one visit and self-injection, and physician-office follow-up. A program was implemented at Burnaby Hospital in May 1996 using the medical day care clinic model as a pilot. Formal evaluation of the program is still in progress but interim evaluation demonstrated overwhelming success.
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