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Published on: May 24, 2016
Cutaneous malignant melanoma metastatic to the eyelid
M E Hartstein1, B Biesman, M C Kincaid
1New England Eye Center, Tufts University School of Medicine, Boston, MA, USA.
Abstract:
Cutaneous malignant melanoma metastatic to the choroid, orbit, or vitreous is rare. Metastatic lesions to the eyelid are rare as well. The authors report a case of malignant melanoma metastatic to the eyelid. This was the first sign of tumor recurrence in a patient who was thought to have been successfully treated for a melanoma of the back 3 years previously. The patient died 6 weeks after diagnosis of the eyelid lesion. In the presence of known malignancy, metastasis must be suspected in new eyelid lesions.
Insights
Malignant melanoma rarely spreads to the eyelid, but this case highlights it as a potential first sign of recurrence. Early suspicion of metastasis is crucial in patients with a history of skin cancer.
Area of Science:
- Ophthalmology
- Oncology
- Dermatology
Background:
- Cutaneous malignant melanoma (CMM) is a significant skin cancer.
- Metastasis of CMM to ocular and orbital structures is uncommon.
- Eyelid metastasis from CMM is exceptionally rare.
Observation:
- A patient with a history of treated melanoma presented with a new eyelid lesion.
- This eyelid lesion was the initial indicator of tumor recurrence.
- The patient had no prior history of ocular or orbital melanoma metastasis.
Findings:
- The eyelid lesion was diagnosed as metastatic malignant melanoma.
- This represented the first sign of recurrence 3 years after initial treatment for a back melanoma.
- The patient's prognosis was poor, with death occurring 6 weeks post-diagnosis.
Implications:
- New eyelid lesions in patients with known malignancy should raise suspicion for metastasis.
- Metastatic melanoma to the eyelid, though rare, can be an early sign of systemic recurrence.
- Timely diagnosis and management are critical for patients with suspected melanoma metastasis.
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