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Primary cutaneous adenoid cystic carcinoma with lymph node metastasis
N Kato1, K Yasukawa, T Onozuka
1Department of Dermatology and Clinical Research Institute, National Sapporo Hospital, Sapporo, Japan.
The American Journal of Dermatopathology
|December 17, 1998
Summary
This case study details primary cutaneous adenoid cystic carcinoma, a rare skin cancer. It highlights the importance of multimodal treatment due to its aggressive nature, local recurrence, and potential for metastasis.
Area of Science:
- Dermatology
- Oncology
Background:
- Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare malignancy.
- This report presents a case of PCACC with subsequent local recurrence and lymph node metastasis.
Observation:
- A 52-year-old Japanese woman presented with a scalp nodule.
- Three and a half years post-treatment (surgery and irradiation), she developed a recurrent scalp lesion and left retroauricular lymph node metastasis.
Findings:
- PCACC has a reported average age of onset of 58.1 years, with a female predilection.
- The scalp is a common site (32%), with a significant local recurrence rate (51%).
- Lymph node metastasis is rare, documented in only two cases, including this one.
Implications:
- PCACC is locally aggressive and can metastasize.
- Multimodal treatment strategies, including surgery, irradiation, and chemotherapy, are recommended.
- This case underscores the need for vigilant follow-up due to recurrence and metastatic potential.