Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Decrease in the high frequency QRS components depending on the local conduction delay

T Watanabe1, M Yamaki, H Tachibana

  • 1First Department of Internal Medicine, Yamagata University School of Medicine, Japan. tewatana@med.id.yamagata-u.ac.jp

Japanese Circulation Journal
|December 18, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer's Disease.

The journal of prevention of Alzheimer's disease·2021
Same author

SU-E-T-555: Weighted Four-Dimensional IMRT Planning for Dynamic MLC Tracking Using a Practical and Simple Framework.

Medical physics·2017
Same author

SU-E-J-165: Development of a Low-Cost and Clinically Available Patient Intrafraction Motion Monitoring System.

Medical physics·2017
Same author

Trapping of excess energy in a nano-layered microenvironment to promote chemical reactions.

Physical chemistry chemical physics : PCCP·2017
Same author

FOXO3 is essential for CD44 expression in pancreatic cancer cells.

Oncogene·2016
Same author

Interactions of Dietary Fats and Proteins on Fatty Acid Composition of Immune Cells and LTB4 Production by Peritoneal Exudate Cells of Rats.

Bioscience, biotechnology, and biochemistry·2016

Conduction delays decrease high-frequency QRS components (HF-QRS), a marker for sudden cardiac death risk. This study confirms HF-QRS reduction indicates disturbed local cardiac conduction.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Signal Processing

Background:

  • High-frequency QRS components (HF-QRS) are linked to sudden cardiac death risk.
  • The relationship between cardiac conduction delay and HF-QRS levels remains debated.

Purpose of the Study:

  • To investigate the impact of slowed local cardiac conduction on HF-QRS.
  • To determine if HF-QRS can serve as an indicator of impaired ventricular conduction.

Main Methods:

  • Utilized 21 dogs with induced cardiac conduction delays via flecainide, lidocaine, or disopyramide infusion.
  • Recorded 60 unipolar electrograms from the ventricular surface.
  • Analyzed filtered (30-250 Hz) QRS signals using fast-Fourier transform to calculate HF-QRS and activation time (AT).

Related Experiment Videos

Main Results:

  • Conduction delay, measured by increased AT, significantly reduced HF-QRS in the affected area.
  • A strong positive correlation was observed between increased AT and decreased HF-QRS (r=0.75-0.83, p<0.001).
  • The reduction in HF-QRS was linearly related to the degree of local conduction delay.

Conclusions:

  • Local cardiac conduction delay demonstrably decreases HF-QRS.
  • HF-QRS is a sensitive indicator of disturbed local cardiac conduction and potential arrhythmia substrate.