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Association between anxiety disorders and a functional polymorphism in the serotonin transporter gene
1Department of Psychiatry, Hamamatsu University School of Medicine, Japan.
Psychiatry Research
|December 19, 1998
Abstract:
Recently, individuals with the short form of the serotonin transporter were found to be associated with neurotic characteristics. An association study on this polymorphism was performed in anxiety disorder patients and control subjects. The short form allele frequency in patients tended to be higher than that in control subjects (81.7 vs. 74.5%). Although it is difficult to ascribe significance to these 'tendencies', these data may suggest that variation of this functional polymorphism makes some contribution to anxiety disorders.