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Cerebral candidiasis in a child 1 year after leukaemia
D A Tweddle1, J C Graham, G S Shankland
1Department of Child Health, Royal Victoria Infirmary, University of Newcastle, Newcastle upon Tyne.
British Journal of Haematology
|December 19, 1998
Abstract:
We describe an unusual case of a late presentation of a fungal brain abscess in a non-neutropenic child 1 year after completing chemotherapy for M5 acute myeloid leukaemia (AML). Biopsy of the mass identified candidal hyphae and the patient was treated with 5 mg/kg of liposomal amphotericin B for 6 weeks. The lesion resolved completely and the child remains well 2 years later. Invasive fungal infection should be included in the differential diagnosis of unexplained symptoms in patients who have previously received intensive chemotherapy.