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Updated: Oct 26, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Chronic childhood illness and maternal mental health--why should we care?
1National Jewish Medical and Research Center, Denver, Colorado 80206, USA.
Insights
Parental emotional distress and social support significantly impact families managing childhood asthma. These factors are key to understanding the family
Area of Science:
- Pediatric pulmonology
- Family medicine
- Psychosomatic medicine
Background:
- Childhood asthma presents significant challenges for families.
- Understanding factors influencing family impact is crucial for effective support.
Purpose of the Study:
- To identify key factors affecting the family impact of childhood asthma.
- To analyze the influence of illness severity, socioeconomic status, and psychosocial factors.
Main Methods:
- Evaluated 70 children/families with asthma at a tertiary-care hospital.
- Utilized stepwise multiple regression analysis.
- Assessed illness severity, socioeconomic status, social support, and parental psychological distress.
Main Results:
- Parental psychological distress, specifically the Psychiatric Symptom Index, was a significant predictor of family impact.
- Social support also emerged as a crucial factor influencing family burden.
- Illness severity and socioeconomic status were not significant predictors in this cohort.
Conclusions:
- Parental emotional well-being and social support are paramount in mitigating the family impact of childhood asthma.
- Interventions should focus on supporting parental mental health and enhancing social networks.
- Further research can explore tailored support strategies for families affected by childhood asthma.
Abstract:
This study evaluated which factors most influenced the impact of childhood asthma on the child's family. Seventy children/families seen at a tertiary-care hospital for asthma were evaluated. Stepwise multiple regression examined the effects of illness severity; family socioeconomic status (SES); family structure; social support; child's emotional characteristics; parent's health; family functioning; and maternal psychological distress on the Family Impact of Illness Scale. Analysis indicated that only the parent's Psychiatric Symptom Index significantly predicted impact scores. The most important predictors of how much impact a child's asthma has on the family are parental emotional distress and amount of social support.
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